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Archive for January, 2006

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Scientists, Linking Gene With Serotonin And Depression, Offer Insights To New Treatments

Sunday, January 8th, 2006

For the more than 18 million Americans who suffer from depressive illnesses, the best pharmacological treatments are those that increase levels of serotonin, the brain chemical that regulates mood, sleep and memory. New research by an international team of scientists, led by Rockefeller University researchers in Paul Greengard’s laboratory of Molecular and Cellular Neuroscience, shows that a gene called p11 is closely related to serotonin transmission in the brain — and may play a key role in determining a person’s susceptibility to depression… click link for more info.

Income Level May Predict Response To Depression Treatment

Wednesday, January 4th, 2006

Low-income people with depression are less likely to respond to treatment and more likely to be suicidal than those who have higher incomes, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals. Socioeconomic factors, including income, education and occupation, have long been linked to health status, illness and death… click link for more info.

Initial Results Help Clinicians Identify Patients With Treatment-resistant Depression

Tuesday, January 3rd, 2006

Initial results of the USA’s largest clinical trial for depression have helped clinicians to track “real world” patients who became symptom-free and to identify those who were resistant to the initial treatment. Participants treated in both medical and specialty mental health care settings experienced a remission of symptoms in 12 to 14 weeks during well-monitored treatment with an antidepressant medication… click link for more info.

Perception Of Remission From Depression - Patients And Researchers Differ

Tuesday, January 3rd, 2006

A study from Rhode Island Hospital shows that patients and clinical researchers may have different criteria for defining remission from depression. Depressed patients measure remission based on how they feel; researchers analyze the number of depressive symptoms in order to gauge whether patients are better… click link for more info.

Suicide Risk Does Not Increase When Adults Start Using Antidepressants, Study Finds

Tuesday, January 3rd, 2006

The risk of serious suicide attempts or death by suicide generally decreases in the weeks after patients start taking antidepressant medication, according to a new study led by Group Health Cooperative researchers and published in the January issue of The American Journal of Psychiatry. The study also found that the risk of suicidal behavior after starting 10 newer antidepressant medications is less than the risk posed by older medications… click link for more info.

Initial Results Help Clinicians Identify Patients With Treatment-resistant Depression

Tuesday, January 3rd, 2006

Initial results of the USA’s largest clinical trial for depression have helped clinicians to track “real world” patients who became symptom-free and to identify those who were resistant to the initial treatment. Participants treated in both medical and specialty mental health care settings experienced a remission of symptoms in 12 to 14 weeks during well-monitored treatment with an antidepressant medication… click link for more info.

Perception Of Remission From Depression - Patients And Researchers Differ

Tuesday, January 3rd, 2006

A study from Rhode Island Hospital shows that patients and clinical researchers may have different criteria for defining remission from depression. Depressed patients measure remission based on how they feel; researchers analyze the number of depressive symptoms in order to gauge whether patients are better… click link for more info.

Suicide Risk Does Not Increase When Adults Start Using Antidepressants, Study Finds

Tuesday, January 3rd, 2006

The risk of serious suicide attempts or death by suicide generally decreases in the weeks after patients start taking antidepressant medication, according to a new study led by Group Health Cooperative researchers and published in the January issue of The American Journal of Psychiatry. The study also found that the risk of suicidal behavior after starting 10 newer antidepressant medications is less than the risk posed by older medications… click link for more info.

STAR*D, A Landmark Depression Study Releases Results

Monday, January 2nd, 2006

The results of the “Sequenced Treatment Alternatives to Relieve Depression” (STAR*D) study are being released in the January 2006 edition of the American Journal Of Psychiatry (AJP), a monthly psychiatric journal of the American Psychiatric Association (APA). The AJP article, Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice, finds that only 30 percent of chronically depressed patients achieve remission during initial treatment with the selective serotonin reuptake inhibitor (SSRI) citalopram… click link for more info.

FDA Warning On Antidepressants Challenged By Long-Term, Population-Based “Suicide Risk During Antidepressant Treatment” Study

Monday, January 2nd, 2006

A 10-year population-based study in the January 2006 edition of the AMERICAN JOURNAL OF PSYCHIATRY (AJP), a monthly psychiatric journal of the American Psychiatric Association (APA), challenges the U.S. Food and Drug Administration (FDA) warning that that suicidal behavior may emerge after treatment is begun with antidepressant medications… click link for more info.

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