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Archive for May, 2006

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What Does Prozac Target?

Thursday, May 18th, 2006

Researchers at Cold Spring Harbor Laboratory on Long Island have identified which among several different kinds of cells in the brain is the chief target of the widely prescribed antidepressant Prozac. This discovery might enable a new generation of more specific treatments for depression, with fewer side effects, to be developed. [click link for full article]

End Of The ‘Prozac Nation’ - More Counselling, More Therapy, Less Medication To Treat Depression, UK

Tuesday, May 16th, 2006

People suffering from depression will be able to have better accessto counselling and talking therapies under a major new programmeannounced today by UK Health Secretary Patricia Hewitt. At the moment many people with mild to moderate depression find itdifficult to access talking therapies, with services patchily spreadacross the country. [click link for full article]

Mechanism Of Lithium Action For The Treatment Of Bipolar Disorder

Monday, May 15th, 2006

Calcium is a common intracellular signaling molecule with a wide range of functions in the brain, and the regulation as well as dysregulation of calcium signaling via the principal intracellular calcium release channel, InsP3R1, has been linked to many normal cellular processes as well as neurological diseases. In addition, the calcium binding protein, neuronal calcium sensor-1 (NCS-1), has been shown to regulate calcium signaling and NCS-1 expression is increased in bipolar patients. [click link for full article]

Mechanism Of Lithium Action For The Treatment Of Bipolar Disorder

Monday, May 15th, 2006

Calcium is a common intracellular signaling molecule with a wide range of functions in the brain, and the regulation as well as dysregulation of calcium signaling via the principal intracellular calcium release channel, InsP3R1, has been linked to many normal cellular processes as well as neurological diseases. In addition, the calcium binding protein, neuronal calcium sensor-1 (NCS-1), has been shown to regulate calcium signaling and NCS-1 expression is increased in bipolar patients. [click link for full article]

A New Approach To Exploring The Genetics Of Suicidal Behaviour

Sunday, May 14th, 2006

“A deeper understanding of the biology of suicidal behavior may facilitate the development of new pharmacological interventions that could be targeted at vulnerable individuals, potentially saving thousands of lives,” say Jonathan Savitz and colleagues from the University of Cape Town. Identifying the genes that contribute to the risk for suicidal behavior is an integral part of this process, say the authors. [click link for full article]

A New Approach To Exploring The Genetics Of Suicidal Behaviour

Sunday, May 14th, 2006

“A deeper understanding of the biology of suicidal behavior may facilitate the development of new pharmacological interventions that could be targeted at vulnerable individuals, potentially saving thousands of lives,” say Jonathan Savitz and colleagues from the University of Cape Town. Identifying the genes that contribute to the risk for suicidal behavior is an integral part of this process, say the authors. [click link for full article]

Paxil Raises Suicide Risk For Young Adults

Saturday, May 13th, 2006

GlaxoSmithkline, the makers of the antidepressant, Paxil, have warned that the drug may raise the risk of suicide attempts in people under 30. Glaxo has sent a letter to doctors stating this. According to a clinical trial, of 3,455 people taking Paxil 11 tried to kill themselves. Among the placebo group of 1,978 people, 1 tried to commit suicide. The majority of suicide attempts were made by patients under 30. One of the Paxil patients who attempted suicide succeeded. [click link for full article]

Antidepressant Drug May Prevent Recurrence Of Depression In Patients With Diabetes

Friday, May 12th, 2006

A team of researchers at Washington University School of Medicine in St. Louis found that an antidepressant medication may reduce the risk of recurrent depression and increase the length of time between depressive episodes in patients with diabetes.”That’s important not only because people with diabetes will feel better if we can control their depression. It’s also key to helping manage blood sugar,” says Patrick J. Lustman, Ph.D. [click link for full article]

National Children’s Depression Awareness Day

Friday, May 12th, 2006

The American Academy of Child and Adolescent Psychiatry (AACAP) joins allied children’s mental health organizations in supporting National Childhood Depression Awareness Day. Depression is an illness that can affect every part of a young person’s life and that of his or her family. As many as one in eight adolescents and one in 33 children have depression. [click link for full article]

Melatonin Improves Mood In Winter Depression

Friday, May 12th, 2006

Researchers at Oregon Health & Science University(OHSU) have found that melatonin, a naturally occurring brain substance, can relieve the doldrums of winter depression, also known as seasonal affective disorder, or SAD. The study is publishing online this week in the Proceedings of the National Academy of Science.The study was led by Alfred Lewy, M.D., Ph.D. [click link for full article]

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