Depressed Jane

DALLAS, March 21, 2006. Children whose mothers are depressed are more likely to suffer from anxiety, mental-health problems and disruptive behavior than those whose moms aren’t. And if the mothers don’t get better, these kids’ problems often become worse, new research shows.Conversely, however, children whose mothers are successfully treated for their depressive symptoms show significant improvements themselves – without any additional intervention or treatment of their own. [click link for full article]

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If a first antidepressant medication doesn’t work, try a different one, UT Southwestern Medical Center researchers report.New research shows that one in three to four people who do not achieve a full remission of symptoms from an initial antidepressant became symptom-free after changing to or adding a second antidepressant. [click link for full article]

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Results of the nation’s largest depression study show that one in three depressed patients who previously did not achieve remission using an antidepressant became symptom-free with the help of an additional medication and one in four achieved remission after switching to a different antidepressant. [click link for full article]

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A new study of approximately 500 patients evaluated the safety and efficacy of the antidepressant Cymbalta® (duloxetine HCl) on the core anxiety symptoms in patients with generalized anxiety disorder. Cymbalta significantly reduced core anxiety symptoms and associated painful physical symptoms and improved functional impairment associated with the illness. [click link for full article]

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Use of some antidepressants might reduce the risk of developing colorectal cancer, according to researchers reporting in the April issue of The Lancet Oncology. The antidepressants known as selective serotonin reuptake inhibitors (SSRI) “might inhibit the growth of colorectal tumours”, says lead investigator Prof Jean-Paul Collet (Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada). [click link for full article]

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The Asher Center for the Study and Treatment of Depressive Disorders and the Northwestern University Feinberg School of Medicine, is the only center in the Midwest participating in a national trial called Biomarkers for Rapid Identification of Treatment Effectiveness in Major Depression (BRITE-MD), which seeks to determine the accuracy of brain monitoring technology to predict the effectiveness of various antidepressant medications. [click link for full article]

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Reactions of two brain regions to reading negative words indicate which depressed patients will be helped by cognitive behavior therapy. This finding appears in an article in the April 2006 issue of The American Journal of Psychiatry (AJP), the official journal of the American Psychiatric Association. The relationship is reported by Greg J. Siegle, Ph.D. [click link for full article]

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Women with no history of depression may be at an increased risk of new onset depressive symptoms and disorders as they transition to menopause, according to two studies in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals. [click link for full article]

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Depressed monkeys not only look and act like depressed people, but their central nervous systems have the same characteristics, a finding that could lead to more effective testing of depression treatments.”Brain scans of depressed female monkeys revealed the same underlying neurobiological changes that are found in the brains of depressed people,” said Carol A. Shively, Ph.D., from Wake Forest University School of Medicine. [click link for full article]

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Elderly patients with lesser versions of depression, a group many times larger than those with major depression, are more than five times as likely as healthy patients to descend into major depression within one year, according to a study published today in the Annals of Internal Medicine. The study’s authors believe that perhaps millions of elderly patients who do not meet the criteria for a diagnosis of major depression are indeed depressed, suffering and not being treated for it. [click link for full article]

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