Let Me Tell You More About My Depressed, Miserable Existence
By Depressed Jane on November 14, 2006
Corcept Therapeutics Incorporated (Nasdaq: CORT) announced today that it completed patient enrollment in Study 06, the third of three Phase 3 clinical trials in which CORLUX(R) (mifepristone) is being evaluated for treating the psychotic features of psychotic major depression (PMD). The company expects to announce the results in late February 2007. [click link for full article]
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By Depressed Jane on November 11, 2006
Some patients who experience recurrent depression may benefit from long-term maintenance treatment with anti-depressant medication, according to a new study led by a Virginia Commonwealth University researcher.Major depressive disorder is a recurrent condition that can have a profound impact on an individual’s quality of life. In the United States, approximately 17 percent of individuals will experience major depressive disorder during their lifetime. [click link for full article]
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By Depressed Jane on November 10, 2006
People with mental health problems will have more choice over their treatment under new guidance published by the Department of Health. The document, ‘Our Choices in Mental Health’, sets out the national framework that will make more choice available locally to people who use mental health services in England. [click link for full article]
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By Depressed Jane on November 10, 2006
Targacept, Inc. (Nasdaq: TRGT) today reported positive results from a double blind, placebo controlled Phase II clinical trial of mecamylamine hydrochloride as an augmentation treatment for major depression. The trial (n=184) evaluated the effects of mecamylamine taken with citalopram hydrobromide, a treatment combination known as TRIDMAC, in patients who did not respond adequately to citalopram alone. [click link for full article]
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By Depressed Jane on November 10, 2006
Barr Pharmaceuticals, Inc. (NYSE: BRL) today announced that its subsidiary, Barr Laboratories, Inc. has received tentative approval from the U.S. Food and Drug Administration (FDA) for its generic version of Eli Lilly and Company’s ZYPREXA(R) Zydis(R) (Olanzapine) Orally Disintegrating Tablets, 5mg, 10mg, 15mg and 20mg. The Company anticipates receiving final approval following the expiration of the 30-month stay in April 2007. [click link for full article]
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By Depressed Jane on November 8, 2006
Infant abuse may be perpetuated between generations by changes in the brain induced by early experience, research shows at the University of Chicago shows.A research team found that when baby rhesus monkeys endured high rates of maternal rejection and mild abuse in their first month of life, their brains often produced less serotonin, a chemical that transmits impulses in the brain. [click link for full article]
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By Depressed Jane on November 7, 2006
A new study released today by the Centre for Addiction and Mental Heath (CAMH) provides a thorough explanation of how the “chemical imbalance” occurs in major depression, a disease that impacts approximately 5 percent of people globally. For over 30 years, scientists believed that monoamines — mood-related chemicals such as serotonin, norepinephrine and dopamine — are low in the brain during major depressive episodes. This is commonly referred to as a “chemical imbalance”. [click link for full article]
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By Depressed Jane on November 6, 2006
Brain imaging researchers at Weill Cornell Medical College in New York City have demonstrated dysfunction in a key brain region in major depression. Major depression, a mood disorder affecting millions of people, causes tremendous suffering with a large impact on public health. Brain imaging has recently produced significant advances concerning brain circuitry in major depression, mostly focusing upon negative emotion and mood regulation. [click link for full article]
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By Depressed Jane on November 6, 2006
Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one — or right combination — is, at times, a matter of trial and error. Studies released earlier this year demonstrated that around 60 percent of patients are not helped by the first drug they are given. [click link for full article]
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By Depressed Jane on November 6, 2006
More than two-thirds of people who suffer from major depression can become symptom-free if they are willing to work with their doctors and try various treatments to determine which work best for them, which may involve taking different antidepressants or adding cognitive therapy to the mix. [click link for full article]
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