Depressed Jane

Let Me Tell You More About My Depressed, Miserable Existence

Archive for March, 2007

More effective medicines with fewer side effects are in the development pipeline and better understanding of the various causes of depression is improving treatment, according to a report issued today by the Association of the British Pharmaceutical Industry (ABPI). [click link for full article]

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Antidepressants increase the presence of a growth factor in the brain, which then leads to a proliferation of new cells, according to a study by Yale School of Medicine researchers in this week’s Proceedings of the National Academy of Sciences. The study describes for the first time the molecular mechanisms and the identity of the protein, vascular endothelial growth factor (VEGF), which underlie the actions of antidepressants on new cell growth and behavior. [click link for full article]

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Depression in elderly people is causing early mortality, a University of Liverpool study has found. In a project involving more than 300 elderly people who had been discharged from hospital, 17% were found to have previously undiagnosed depression and of that figure, 7% died within two years of leaving hospital. [click link for full article]

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A woman’s breast cancer diagnosis can wreak as much havoc on her emotions as it does on her physical health. Mothers who experience bouts of depression during their battles with breast cancer may find that the effects reach beyond their own psyches to those of their children. [click link for full article]

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According to a review in Annals of the New York Academy of Sciences, evidence is mounting that lifelong stress-related conditions such as depression and chronic pain may be linked to fetal growth and timing of delivery. [click link for full article]

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Rates of major depression are higher among whites, but the condition appears more likely to be severe, untreated and disabling among blacks, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.Major depression is the fourth leading cause of disability worldwide, according to background information in the article. [click link for full article]

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1. Anxiety Disorders Are Common in Primary Care and Much Undertreated A study of 965 patients in a primary care setting found that nearly 20 percent had at least one of four main anxiety disorders and many had more than one anxiety disorder (Article, p. 317). Further, 41 percent of the patients with an anxiety disorder were not receiving treatment. [click link for full article]

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Antidepressant treatment appears to help stroke survivors with the kind of complex mental abilities often referred to as “thinking outside the box,” according to a University of Iowa study.The antidepressants’ effects on study participants’ abilities were independent of any changes in depression. In addition, the improvements in complex mental abilities were not seen immediately but during the course of 21 months after the treatment ended. [click link for full article]

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Systemic lupus erythomatosus (SLE), often simply called lupus, is a complex autoimmune disease marked by joint pain, skin rashes, extreme fatigue, and depression, among other symptoms. Some studies have described a possible link between SLE’s most severe psychiatric manifestation, psychosis, and a protein autoantibody associated with the central nervous system, anti-ribosomal P. [click link for full article]

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According to a review in Annals of the New York Academy of Sciences, evidence is mounting that lifelong stress-related conditions such as depression and chronic pain may be linked to fetal growth and timing of delivery. [click link for full article]

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