Depressed Jane

Exercise has a similar effect to antidepressants on depression. This has been shown by previous research. Now Astrid Bjornebekk at Karolinska Institutet has explained how this can happen: exercise stimulates the production of new brain cells.In a series of scientific reports, she has searched for the underlying biological mechanisms that explain why exercise can be a form of therapy for depression and has also compared it with pharmacological treatment with an SSRI drug. [click link for full article]

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Antidepressants lower the risk of suicide attempt in adults with depression, according to a study published in the July issue of the American Journal of Psychiatry. The researchers also found that the lower risk held true for young adults ages 18 to 25. [click link for full article]

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In a study of more than 100,000 patients treated for depression, suicide attempts declined during the first month of treatment – whether that treatment consisted of medication, psychotherapy, or both. The findings, published by Group Health researchers in the July American Journal of Psychiatry, show a similar pattern for populations of adolescents and young adults (up to age 24) as for older adults.The study sheds new light on the “black box” advisory that the U.S. [click link for full article]

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Organon, the human healthcare business unit of Akzo Nobel and Meiji Seika Kaisha has announced the filing of the new drug application for the novel antidepressant mirtazapine (also known as Remeron®) to the Japanese health authorities (PMDA). Mirtazapine – a Noradrenergic and Specific Serotonergic Antidepressant (NaSSA) – has a different mechanism of action and has been proven safe and effective in the treatment of major depression in more than 80 countries worldwide. [click link for full article]

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The class of antidepressant medications known as selective serotonin reuptake inhibitors may be associated with an increased rate of bone loss in older men and women, according to two articles in the June 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. [click link for full article]

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The American Association of Kidney Patients (AAKP) announced the development of two new depression brochures. Understanding Depression in Kidney Disease is the latest addition to the AAKP Understanding series. It is accompanied by When Your Loved One is Depressed, Tips on How You Can Help. Nearly 30 million Americans suffer from some form of depression. Many people with depression do not seek help, even though most of those with severe cases can be helped. [click link for full article]

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Scientists’ hunt for the cause of depression has implicated so many suspects and found so many treatments with different mechanisms that the condition remains an enigma. Now researchers at the Stanford University School of Medicine have identified one unifying principle that could explain how a range of causes and treatments for depression converge. [click link for full article]

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High-speed camera snapshots may have pinpointed a spot in the brain that serves as a marker for depression. Investigators have observed that electrical chatter in the dentate gyrus-a C-shaped region of the hippocampus-contracts in depressed rats but expands again after the animals receive antidepressants. [click link for full article]

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Patients with depression treated in two independent health care systems experienced overall drops in suicide attempts between the month prior to starting treatment with antidepressant medications and the month after treatment began. The findings are based on records from a large prepaid health plan and from Veterans Health Administration databases, reflecting the clinical care of more than 330,000 patients. [click link for full article]

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Treating people with depression — by means of either medications or psychotherapy — leads to a drop in suicide attempts, according to a new report. The findings relate to the controversy about treating young people with antidepressant drugs, and the suspicion that doing so may be linked to increased suicide rates. [click link for full article]

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