Depressed Jane

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Archive for December, 2007

Aspect Medical Systems, Inc. (NASDAQ: ASPM) announced that study results from the BRITE (Biomarkers for Rapid Identification of Treatment Effectiveness) trial in major depression demonstrate that the company’s EEG-based Antidepressant Treatment Response (ATR) indicator is a significant predictor of patient response and remission from depression when utilized one week following initiation of treatment with escitalopram. [click link for full article]

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Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains. This new study reports findings that support the evaluation of a potential new antidepressant agent. [click link for full article]

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Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), announces that data from two Phase 3 clinical studies of PRISTIQ(TM) (desvenlafaxine), an investigational serotonin-norepinephrine reuptake inhibitor (SNRI), showed that adult patients who received a 50 mg/day dose of PRISTIQ for the treatment of major depressive disorder (MDD) experienced a statistically significant reduction in the symptoms of major depression compared to placebo. [click link for full article]

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Countless movies and TV shows make light of women’s so-called “moodiness”, often jokingly attributing it to their menstrual cycle or, conversely, to menopause. In fact, mood disorders are a serious and pervasive health problem, and large-scale population studies have found women are 1.5 to 3 times more likely to suffer from major depressive disorder than are men. [click link for full article]

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Major depressive disorder (MDD) is the most common major mental illness, afflicting almost one in five individuals. More than 75% of people who recover from an episode of MDD will have at least one recurrence, with the majority having multiple recurrences. MDD is the leading cause of disability of all medical illnesses, with substantial functional impairment, morbidity, and mortality. [click link for full article]

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The first data from the SEROQUEL XL® major depressive disorder (MDD)1,2 and generalised anxiety disorder (GAD)3 clinical development programmes were presented at the 7th International Forum on Mood and Anxiety Disorders (IFMAD) in Budapest. [click link for full article]

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Depression is known to be associated with cancer yet too many cancer patients are not screened for this mental disorder, according to researchers from the Indiana University School of Medicine, the Regenstrief Institute and the Roudebush VA Medical Center. In a study published in the November-December issue of General Hospital Psychiatry, Caroline Carney Doebbeling, M.D., M.Sc. and Laura Jones, Ph.D. [click link for full article]

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The 2007 American College of Neuropsychopharmacology Annual Meeting featured hundreds of new studies on brain and behavior from the world’s leading scientists. Presentations included innovative research on potential new treatments for depression, post-traumatic stress disorder, autism and addiction. [click link for full article]

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Psychiatrists remain divided as to how to define and classify the mood and anxiety disorders, the most common mental disorders. Committees across the globe are currently pondering how best to carve nature at its anxious joints for the fifth version of the Diagnostic and Statistical Manual (DSM-V), the “gold standard” reference book for psychiatrists. Only recently has the process of refining the diagnostic system been informed by high quality longitudinal data. [click link for full article]

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As in most fields of medicine, psychiatry researchers are working to identify specific types of patients, through their individual genetic variations, that may better benefit from particular drugs or combinations of drugs than other patients. [click link for full article]

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