Depressed Jane

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains. This new study reports findings that support the evaluation of a potential new antidepressant agent. [click link for full article]

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Psychiatrists remain divided as to how to define and classify the mood and anxiety disorders, the most common mental disorders. Committees across the globe are currently pondering how best to carve nature at its anxious joints for the fifth version of the Diagnostic and Statistical Manual (DSM-V), the “gold standard” reference book for psychiatrists. Only recently has the process of refining the diagnostic system been informed by high quality longitudinal data. [click link for full article]

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The 2007 American College of Neuropsychopharmacology Annual Meeting featured hundreds of new studies on brain and behavior from the world’s leading scientists. Presentations included innovative research on potential new treatments for depression, post-traumatic stress disorder, autism and addiction. [click link for full article]

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Depression is known to be associated with cancer yet too many cancer patients are not screened for this mental disorder, according to researchers from the Indiana University School of Medicine, the Regenstrief Institute and the Roudebush VA Medical Center. In a study published in the November-December issue of General Hospital Psychiatry, Caroline Carney Doebbeling, M.D., M.Sc. and Laura Jones, Ph.D. [click link for full article]

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Depression nearly triples the risk of death following a heart attack, even when accounting for other heart attack risk factors, according to research presented at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depression in the first six months were more than twice as likely to die. [click link for full article]

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Researchers may be able to develop an antidepressant which takes effect almost immediately by directly targeting novel molecules in the brain instead of taking a less direct route, which can lead to longer times for medication to take effect, according to a new study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting. The antidepressant is also thought to be effective in people for whom previous treatments have been ineffective. [click link for full article]

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As in most fields of medicine, psychiatry researchers are working to identify specific types of patients, through their individual genetic variations, that may better benefit from particular drugs or combinations of drugs than other patients. [click link for full article]

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A woman who suffers from depression is more likely to reach the menopause with a higher risk of bone fractures (osteoporosis), compared to a woman who does not have depression. In a study published inArchives of Internal Medicine it was found that 17% of women with depression had less bone mass in a section of their hip, called the femoral neck, compared to 2% of women who did not have depression. [click link for full article]

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Researchers at the University of Pennsylvania School of Medicine report that older adults with diabetes and depression are half as likely to die over a 5-year period when they receive depression care management than depressed patients with diabetes who do not receive depression care management. The first known study to examine the relationship between diabetes and mortality in a depression intervention trial appears in the December issue of Diabetes Care. [click link for full article]

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The first data from the SEROQUEL XR™ (quetiapine fumarate) Extended Release clinical development programme in major depressive disorder (MDD)1,2 and generalised anxiety disorder (GAD)3 were presented at the 7th International Forum on Mood and Anxiety Disorders (IFMAD) in Budapest, AstraZeneca announced today. [click link for full article]

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