Depressed Jane

Let Me Tell You More About My Depressed, Miserable Existence

Archive for July, 2008

New data from a study of patients with treatment-resistant depression who underwent deep brain stimulation (DBS) in the subcallosal cingulate region (SCG or Cg25) of the brain shows that this intervention is generally safe and provides significant improvement in patients as early as one month after treatment. The patients also experienced continued and sustained improvement over time.

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Patients with accident or trauma related chronic pain often have post-traumatic stress disorder (PTSD) and depression. What isn’t clearly known, however, is how PTSD relates to mood disorders and pain severity in chronic pain patients. University of Michigan researchers examined the contribution of PTSD to the pain experience, functional disability and frequency of depressive symptoms.

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The Health Department today announced a new online campaign to engage teenagers grappling with depression, drugs, and violence, and to encourage them to seek help. NYC Teen Mindspace, posted on MySpace, is the agency’s first effort to promote health through Web-based social networking – a medium with great potential because of its popularity with young people. To see the campaign, visit www.myspace.

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Patients suffering from major depression are at an increased risk for cardiovascular disease, but treating these patients with medication can greatly reduce the risk, according to new findings by researchers at the University of Miami Miller School of Medicine. The results of their study are published in the July 16 issue of the journal PLoS ONE.

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To ease pain and numbness associated with diabetes, NewYork-Presbyterian/Weill Cornell physician-scientists are studying a drug previously used for depression to treat peripheral neuropathy. Diabetics often suffer from this condition because of high blood sugar levels that damage nerve cells. Those with peripheral neuropathy often endure chronic pain, cramping and sleepless nights that prevent them from living a normal lifestyle.

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Decision Resources, one of the world’s leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that a drug’s long-term efficacy in preventing recurrence of depressive mood episodes in patients who suffer from major depressive disorder, is the attribute that most influences psychiatrists’ prescribing decisions in the treatment of this disorder.

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Depression And Antidepressants Increase Risk Of Falling In Later Life Older people have a high risk for falls and the ensuing injuries. This risk, according to an article released on June 17, 2008 in the open-access journal PLoS ONE, is increased by the presence of depression, and increased even more with medication for depression. Falls are a common problem in seniors, who often have impaired reflexes and strength.

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The expectation that East-Asian people emphasize physical symptoms of depression (e.g. headaches, poor appetite or aches/pains in the body) is widely acknowledged, yet the few available empirical studies report mixed data on this issue. A new study from the Centre for Addiction and Mental Health (CAMH) debunks this cultural myth, and offers clinicians valuable insight to into cultural context when assessing a patient, leading to more accurate diagnosis.

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A new Mayo Clinic study shows that variations in the serotonin transporter gene could explain why some people with depression respond better than others to treatment with citalopram (Celexa), an antidepressant medication. The study, in the current issue of the American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, examined the serotonin transporter gene, or SLC6A4, in 1,914 study participants.

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TheraGenetics Limited, a personalized medicine diagnostics company that is developing and commercializing a portfolio of pharmacogenetic diagnostic tests to guide and improve the treatment of central nervous system (CNS) disorders, announced that it has completed an agreement with the Centre for

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