Depressed Jane

Let Me Tell You More About My Depressed, Miserable Existence

Archive for February, 2009

Rexahn Pharmaceuticals, Inc. (NYSE Alternext US: RNN), a leader in development of innovative therapeutics for life-threatening and life-debilitating diseases, announced today that it has initiated a Phase IIa clinical trial for Serdaxin(TM), for the treatment of major depressive disorder (MDD). The Serdaxin Phase IIa study calls for the recruitment of up to 100 patients to evaluate its preliminary efficacy in treating MDD.

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Your mother’s wrinkles – or lack there of, may not be the best predictor of how you’ll age. In fact, a new study claims just the opposite. The study, involving identical twins, suggests that despite genetic make-up, certain environmental factors can add years to a person’s perceived age.

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A thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden, concludes that people who have nightmares following a suicide attempt are five times more likely to attempt suicide again, compared with those who do not have nightmares. The study included 165 patients aged 18-69 years, who were being treated at somatic and psychiatric departments following a suicide attempt in Sweden.

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Rexahn Pharmaceuticals, Inc. (NYSE Alternext US: RNN), a leader in development of innovative therapeutics for life-threatening and life-debilitating diseases, announced today that it has initiated a Phase IIa clinical trial for SerdaxinTM, for the treatment of major depressive disorder (MDD). The Serdaxin Phase IIa study calls for the recruitment of up to 100 patients to evaluate its preliminary efficacy in treating MDD.

Popularity: unranked [?]

Women who have higher levels of a hormone produced by the placenta midway through pregnancy appear more likely to develop postpartum depression, a study authored by a UC Irvine researcher finds. The discovery could help identify and treat women at risk for postpartum depression long before the onset of symptoms.

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Women who have higher levels of a hormone produced by the placenta midway through their pregnancy appear more likely to develop postpartum depression, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals. Postpartum depression (PPD) is more serious than “baby blues” and begins within four to six weeks of giving birth, according to background information in the article.

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Selective serotonin reuptake inhibitors (SSRIs) may reduce the risk of suicide in depressed adults, according to a study by researchers from the World Health Organization and the University of Verona, Italy published in CMAJ. The study, a meta-analysis of 8 large-scale observational studies, was undertaken to explore whether SSRIs reduce or increase the risk of suicide in depressed people. Previous studies, including a 2007 study by the U.S.

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Genes, psychological adversity in childhood, and recent or ongoing psychological stress may combine to cause major depression, write Dr. Sanjay Mathew and colleagues from Mount Sinai School of Medicine in New York in a review published in CMAJ. “Major depressive disorder is thought to result from the complex interplay of multiple inherited factors and subsequent exposure to a wide range of environmental variables through life,” write Dr. Mathew and coauthors.

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A new study has found that the more a teenager is exposed to television and other electronic media the higher are his/her chances of developing depression symptoms in young adulthood – this is especially the case for young men, says a study published in Archives of General Psychiatry, a JAMA/Archives journal. The authors explain that depression is the leading cause of non-fatal disability worldwide. It tends to start during adolescence or young adulthood.

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Major depression (MD) is a severe, life-threatening and widespread psychiatric disorder, which is predicted to soon become one of the major causes of death worldwide. However, despite extensive investigations, the exact mechanisms that lead to MD have not been identified.

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