Depressed Jane

The Saint Louis University Health Sciences Center medical team involved in the research and development of an innovative therapy for depression – vagal nerve stimulation (VNS) – is starting a new clinic for patients who have treatment-resistant depression. The vagal nerve stimulator was approved Friday by the Food and Drug Administration for treatment-resistant depression following clinical trials around the United States, including Saint Louis University… click link for more info.

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Feeling depressed and fatigued does not increase a person’s risk for cancer, according to a new study. Severely exhausted people, however, do engage in behavior that is associated with a higher cancer risk. The study, published in the September 15, 2005 issue of CANCER (http:/www… click link for more info.

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A UCLA imaging study revealed significant tissue loss in the regions of heart-failure patients’ brains that regulate the autonomic nervous system, interfering with the cardiovascular system’s ability to swiftly adapt to changes in blood pressure and heart rate. The damage lies in the same brain areas showing changes in people suffering major depression, which may explain why many heart-failure patients are often depressed… click link for more info.

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New research suggests that depression may hasten the progression of heart disease by increasing the levels of a key protein that causes inflammation. In a study of 32 people with heart failure, the 14 patients who felt the most depressed had nearly twice the levels of this protein in their blood… click link for more info.

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Patients who experience symptoms, such as sleepiness, fatigue, poor motivation, irritability, and difficulty concentrating, are often diagnosed with depression and are treated with antidepressants. A new study suggests that many of these patients have obstructive sleep apnea (OSA), and their symptoms may be reduced with continuous positive airway pressure (CPAP) therapy… click link for more info.

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Two-thirds of depressed patients prefer Remeron SolTab®, a fast dissolving antidepressant tablet to the antidepressant’s conventional tablet formulation. This according to findings, from a unique global research study involving almost 4,000 patients to date, that were recently presented at the American Psychiatric Association (APA) annual meeting in Atlanta… click link for more info.

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The first melatonergic antidepressant, Valdoxan® (agomelatine), offers an innovative new approach to the treatment of depression. Valdoxan combines antidepressant efficacy, even in severely depressed patients, with an extremely favourable side-effect profile and has the additional benefit of sleep regulation in depressive patients, according to new data presented at the 18th Congress of the European College of Neuropsychopharmacology (ECNP) today… click link for more info.

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